Product Brief Introduction
Product name: 3-Morpholinopropanesulfonic acid (MOPS)
CAS No.: 1132-61-2
IUPAC Name: 3-morpholin-4-ylpropane-1-sulfonic acid
Abbreviation: MOPS
EINECS No.: 214-478-5
Molecular Formula: C7H15NO4S
Molecular Weight: 209.26
SMILES: O=S(=O)(O)CCCN1CCOCC1
Basic Overview
MOPS belongs to Good’s zwitterionic biological buffer. Effective buffering pH range: 6.5 ~ 7.9, pKa (25℃)=7.20.
White crystalline powder, freely soluble in water. Low UV absorbance, minimal interference to enzyme reaction & nucleic acid/protein detection. Widely used in biochemistry, cell culture, electrophoresis, molecular biology experiments.
Typical Physical & Chemical Properties
Appearance: White crystalline powder
Melting Point: 277–282 ℃ (decompose)
Solubility: ≥1000 g/L in water (20 ℃)
pH (1M aqueous solution): 3.6 ~ 4.4
Stability: Stable under ambient conditions; avoid strong oxidants
UV Characteristic: Low absorbance at 260 nm & 280 nm
Main Applications
Biochemical buffer for protein purification, enzyme assay
RNA agarose gel electrophoresis running buffer
Mammalian / microbial cell culture medium buffer
Diagnostic kits, nucleic acid extraction reagent raw material
Cosmetic formulation pH stabilizer
Quality specification
| Item | Specification | Test Method |
|---|---|---|
| Appearance | White crystalline powder | Visual Inspection |
| Assay (Titration, dried basis) | ≥99.5 % | Potentiometric Titration |
| Loss on Drying | ≤0.50 % | Gravimetry (105℃) |
| Absorbance (260 nm, 10% w/v) | ≤0.05 | UV Spectrophotometry |
| Absorbance (280 nm, 10% w/v) | ≤0.03 | UV Spectrophotometry |
| Chloride (Cl⁻) | ≤0.005 % | Turbidimetry |
| Sulphate (SO42−) | ≤0.005 % | Turbidimetry |
| Heavy Metals (as Pb) | ≤5 ppm | AAS |
| Residue on Ignition | ≤0.10 % | Gravimetry |
Packing
Package: 25kg fiber drum with inner PE liner
Storage: Sealed, cool & dry warehouse, away from light
Shelf life: 24 months under proper storage
Avoid dust inhalation; wear dust mask & protective gloves
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